Can the Severity of Normal Tissue Damage after Radiation Therapy Be Predicted?

Can the Severity of Normal Tissue Damage after Radiation Therapy Be Predicted?

R adiotherapy can lead to both acute and late side effects, the former occurring over a timescale of weeks and then subsiding. Late effects occur months or even years after cessation of treatment and often show continuous progression with time. With conventionally fractionated radiotherapy, the late side effects usually limit the dose. There are clear differences between patients regarding side...

Normal tissue complications after radiation therapy.

This paper describes the biological mechanisms of normal tissue reactions after radiation therapy, with reference to conventional treatments, new treatments, and treatments in developing countries. It also describes biological reasons for the latency period before tissue complications arise, the relationship of dose to incidence, the effect of increasing the size of the irradiated volume, early...

Histologic severity of appendicitis can be predicted by computed tomography.

HYPOTHESIS A regression model based on computed tomographic (CT) findings alone can accurately predict the histologic severity of acute appendicitis in patients who have a high disease likelihood. DESIGN Retrospective study. SETTING Mayo Clinic in Scottsdale, Ariz. PATIENTS Consecutive sample of 105 patients (50 women and 55 men, aged 15-89 years) undergoing nonincidental appendectomy wit...

Can Cascades be Predicted?

A famous instance is a picture of a receipt taken by a customer at a hunting and fishing chain store called Cabela. The receipt listed a 2.3%“medical excise tax,” which was supposedly levied as part of the Affordable Care Act. This was seen as evidence that there is a hidden tax that consumers are paying for the ACA. The store later cleared this up as being a “software glitch” on their part. Th...

Treatment of radiation-induced normal tissue lesions